This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2xu7
From Proteopedia
(Difference between revisions)
| Line 6: | Line 6: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xu7 RCSB], [http://www.ebi.ac.uk/pdbsum/2xu7 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xu7 RCSB], [http://www.ebi.ac.uk/pdbsum/2xu7 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RBBP4_HUMAN RBBP4_HUMAN]] Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.<ref>PMID:10866654</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Blobel, G A | + | [[Category: Blobel, G A]] |
| - | [[Category: Laue, E D | + | [[Category: Laue, E D]] |
| - | [[Category: Lejon, S | + | [[Category: Lejon, S]] |
| - | [[Category: Mackay, J P | + | [[Category: Mackay, J P]] |
| - | [[Category: Murthy, A | + | [[Category: Murthy, A]] |
| - | [[Category: Murzina, N V | + | [[Category: Murzina, N V]] |
| - | [[Category: Thong, S Y | + | [[Category: Thong, S Y]] |
[[Category: Chromatin remodelling]] | [[Category: Chromatin remodelling]] | ||
[[Category: Corepressor]] | [[Category: Corepressor]] | ||
Revision as of 00:50, 25 December 2014
STRUCTURAL BASIS FOR RBAP48 BINDING TO FOG-1
| |||||||||||
