2ao7

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[[Image:2ao7.gif|left|200px]]<br /><applet load="2ao7" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2ao7.gif|left|200px]]
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caption="2ao7, resolution 2.9&Aring;" />
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'''Adam10 Disintegrin and cysteine- rich domain'''<br />
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{{Structure
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|PDB= 2ao7 |SIZE=350|CAPTION= <scene name='initialview01'>2ao7</scene>, resolution 2.9&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/ADAM10_endopeptidase ADAM10 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.81 3.4.24.81]
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|GENE= ADAM10, MADM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
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}}
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'''Adam10 Disintegrin and cysteine- rich domain'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2AO7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/ADAM10_endopeptidase ADAM10 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.81 3.4.24.81] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AO7 OCA].
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2AO7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AO7 OCA].
==Reference==
==Reference==
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ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16239135 16239135]
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ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16239135 16239135]
[[Category: ADAM10 endopeptidase]]
[[Category: ADAM10 endopeptidase]]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: protease]]
[[Category: protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:51:58 2008''

Revision as of 13:51, 20 March 2008

Image:2ao7.gif


PDB ID 2ao7

Drag the structure with the mouse to rotate
, resolution 2.9Å
Ligands:
Gene: ADAM10, MADM (Bos taurus)
Activity: ADAM10 endopeptidase, with EC number 3.4.24.81
Coordinates: save as pdb, mmCIF, xml



Adam10 Disintegrin and cysteine- rich domain


Overview

Ephrin ligands presented on one cell surface associate with their receptors on the surface of a juxtaposed cell, often resulting in cell-cell repulsion. In this issue of Cell, Janes et al. (2005) show that the ephrin ligand can be proteolytically released from its membrane tether by a complex on the opposing cell composed of the ephrin receptor and an ADAM metalloprotease.

About this Structure

2AO7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:16239135

Page seeded by OCA on Thu Mar 20 15:51:58 2008

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