4ir3

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[[Image:4ir3.jpg|left|200px]]
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==Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone (GSK2833282A)==
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<StructureSection load='4ir3' size='340' side='right' caption='[[4ir3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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{{STRUCTURE_4ir3| PDB=4ir3 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ir3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IR3 FirstGlance]. <br>
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===Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone (GSK2833282A)===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1FK:1-[7-AMINO-1-(PYRIMIDIN-2-YL)INDOLIZIN-3-YL]ETHANONE'>1FK</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ir4|4ir4]], [[4ir5|4ir5]], [[4ir6|4ir6]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ir3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ir3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ir3 RCSB], [http://www.ebi.ac.uk/pdbsum/4ir3 PDBsum]</span></td></tr>
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[[4ir3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR3 OCA].
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Chaikuad, A.]]
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[[Category: Chaikuad, A]]
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[[Category: Chen, P.]]
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[[Category: Chen, P]]
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[[Category: Chung, C W.]]
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[[Category: Chung, C W]]
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[[Category: Delft, F von.]]
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[[Category: Delft, F von]]
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[[Category: Drewry, D.]]
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[[Category: Drewry, D]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Fedorov, O.]]
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[[Category: Fedorov, O]]
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[[Category: Felletar, I.]]
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[[Category: Felletar, I]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Filippakopoulos, P]]
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[[Category: Knapp, S.]]
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[[Category: Knapp, S]]
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[[Category: Krojer, T.]]
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[[Category: Krojer, T]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
[[Category: Acetylated lysine binding protein]]
[[Category: Acetylated lysine binding protein]]
[[Category: Bromodomain]]
[[Category: Bromodomain]]
[[Category: Kiaa1476]]
[[Category: Kiaa1476]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
 
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Walp4]]
[[Category: Walp4]]

Revision as of 01:07, 25 December 2014

Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone (GSK2833282A)

4ir3, resolution 2.00Å

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