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2wu1

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wu1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WU1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WU1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wu1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WU1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WU1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16G:N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE'>16G</scene>, <scene name='pdbligand=FGS:5-(ACETYLAMINO)-5-DEOXY-1-O-PHOSPHONO-L-IDITOL'>FGS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16G:N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE'>16G</scene>, <scene name='pdbligand=FGS:5-(ACETYLAMINO)-5-DEOXY-1-O-PHOSPHONO-L-IDITOL'>FGS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fs5|1fs5]], [[1hot|1hot]], [[1fs6|1fs6]], [[1cd5|1cd5]], [[1frz|1frz]], [[1jt9|1jt9]], [[1fqo|1fqo]], [[1fsf|1fsf]], [[1hor|1hor]], [[1dea|1dea]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fs5|1fs5]], [[1hot|1hot]], [[1fs6|1fs6]], [[1cd5|1cd5]], [[1frz|1frz]], [[1jt9|1jt9]], [[1fqo|1fqo]], [[1fsf|1fsf]], [[1hor|1hor]], [[1dea|1dea]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosamine-6-phosphate_deaminase Glucosamine-6-phosphate deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.99.6 3.5.99.6] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosamine-6-phosphate_deaminase Glucosamine-6-phosphate deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.99.6 3.5.99.6] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wu1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wu1 RCSB], [http://www.ebi.ac.uk/pdbsum/2wu1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wu1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wu1 RCSB], [http://www.ebi.ac.uk/pdbsum/2wu1 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NAGB_ECOLI NAGB_ECOLI]] Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.[HAMAP-Rule:MF_01241]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Glucosamine-6-phosphate deaminase]]
[[Category: Glucosamine-6-phosphate deaminase]]
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[[Category: Horjales, E.]]
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[[Category: Horjales, E]]
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[[Category: Rojas-Trejo, S P.]]
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[[Category: Rojas-Trejo, S P]]
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[[Category: Rudino-Pinera, E.]]
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[[Category: Rudino-Pinera, E]]
[[Category: Aldose-ketose isomerase]]
[[Category: Aldose-ketose isomerase]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]

Revision as of 01:14, 25 December 2014

GLUCOSAMINE-6-PHOSPHATE DEAMINASE COMPLEXED WITH THE ALLOSTERIC ACTIVATOR N-ACETYL-GLUCOAMINE-6-PHOSPHATE BOTH IN THE ACTIVE AND ALLOSTERIC SITES.

2wu1, resolution 2.20Å

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