4j3e

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j3e RCSB], [http://www.ebi.ac.uk/pdbsum/4j3e PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j3e RCSB], [http://www.ebi.ac.uk/pdbsum/4j3e PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MDM2_XENLA MDM2_XENLA]] E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degration by the proteasome (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: African clawed frog]]
[[Category: African clawed frog]]
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[[Category: Crowther, R.]]
+
[[Category: Crowther, R]]
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[[Category: Graves, B J.]]
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[[Category: Graves, B J]]
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[[Category: Kammlott, R U.]]
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[[Category: Kammlott, R U]]
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[[Category: Lukacs, C M.]]
+
[[Category: Lukacs, C M]]
[[Category: E3 ubiquitin ligase]]
[[Category: E3 ubiquitin ligase]]
[[Category: Imidazoline]]
[[Category: Imidazoline]]

Revision as of 01:15, 25 December 2014

The 1.9A crystal structure of humanized Xenopus Mdm2 with nutlin-3a

4j3e, resolution 1.91Å

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