2oq5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2oq5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OQ5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2oq5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OQ5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TMPRSS11E, DESC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TMPRSS11E, DESC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2oq5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2oq5 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TM11E_HUMAN TM11E_HUMAN]] Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Huber, R.]]
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[[Category: Huber, R]]
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[[Category: Kyrieleis, O J.P.]]
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[[Category: Kyrieleis, O J.P]]
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[[Category: Madison, E L.]]
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[[Category: Madison, E L]]
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[[Category: U., Jacob.]]
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[[Category: U., Jacob]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Trypsin-like serine protease]]
[[Category: Trypsin-like serine protease]]
[[Category: Tumor marker]]
[[Category: Tumor marker]]
[[Category: Type ii trans-membrane serine proteinase]]
[[Category: Type ii trans-membrane serine proteinase]]

Revision as of 01:17, 25 December 2014

Crystal structure of DESC1, a new member of the type II transmembrane serine proteinases family

2oq5, resolution 1.61Å

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