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2pji
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2pji]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaz 1xaz]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PJI FirstGlance]. <br> | <table><tr><td colspan='2'>[[2pji]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaz 1xaz]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PJI FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Calloselasma rhodostoma])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Calloselasma rhodostoma])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pji OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pji RCSB], [http://www.ebi.ac.uk/pdbsum/2pji PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pji OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pji RCSB], [http://www.ebi.ac.uk/pdbsum/2pji PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DISR_AGKRH DISR_AGKRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Calloselasma rhodostoma]] | [[Category: Calloselasma rhodostoma]] | ||
| - | [[Category: Chuang, W J | + | [[Category: Chuang, W J]] |
| - | [[Category: Liu, Y C | + | [[Category: Liu, Y C]] |
| - | [[Category: Shiu, J H | + | [[Category: Shiu, J H]] |
[[Category: Disintegrin]] | [[Category: Disintegrin]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Rhodostomin]] | [[Category: Rhodostomin]] | ||
Revision as of 01:17, 25 December 2014
Solution structure of rhodostomin P48A mutant
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