3fb8
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fb8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fb8 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fb8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fb8 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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*[[Antibody|Antibody]] | *[[Antibody|Antibody]] | ||
*[[Potassium Channel|Potassium Channel]] | *[[Potassium Channel|Potassium Channel]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 01:21, 25 December 2014
KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion
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Categories: Mus musculus | Streptomyces lividans | Cortes, D M | Cuello, L G | Jogini, V | Perozo, E | Cell membrane | Inactivation | Ion transport | Ionic channel | Kcsa | Membrane | Membrane protein-metal transport complex | Open | Potassium channel | Transmembrane | Transport | Voltage-gated channel
