4js9
From Proteopedia
(Difference between revisions)
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| - | + | ==Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme== | |
| - | + | <StructureSection load='4js9' size='340' side='right' caption='[[4js9]], [[Resolution|resolution]] 2.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4js9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JS9 FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=MH0:MESOHEME'>MH0</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nod|1nod]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Inosl, Nos2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4js9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4js9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4js9 RCSB], [http://www.ebi.ac.uk/pdbsum/4js9 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/NOS2_MOUSE NOS2_MOUSE]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.<ref>PMID:16373578</ref> | [[http://www.uniprot.org/uniprot/NOS2_MOUSE NOS2_MOUSE]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.<ref>PMID:16373578</ref> | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Lk3 transgenic mice]] | |
| - | <references | + | [[Category: Bolisetty, K]] |
| - | [[Category: Bolisetty, K | + | [[Category: Hannibal, L]] |
| - | [[Category: Hannibal, L | + | [[Category: Misra, S]] |
| - | [[Category: Misra, S | + | [[Category: Page, R C]] |
| - | [[Category: Page, R C | + | [[Category: Stuehr, D J]] |
| - | [[Category: Stuehr, D J | + | [[Category: Yu, Z]] |
| - | [[Category: Yu, Z | + | |
[[Category: Calmodulin-binding]] | [[Category: Calmodulin-binding]] | ||
[[Category: Fad]] | [[Category: Fad]] | ||
Revision as of 01:46, 25 December 2014
Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
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Categories: Lk3 transgenic mice | Bolisetty, K | Hannibal, L | Misra, S | Page, R C | Stuehr, D J | Yu, Z | Calmodulin-binding | Fad | Fmn | Iron | Mesoheme | Metal-binding | Nadp | Oxidoreductase
