1frt

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1frt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1frt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1frt RCSB], [http://www.ebi.ac.uk/pdbsum/1frt PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1frt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1frt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1frt RCSB], [http://www.ebi.ac.uk/pdbsum/1frt PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/FCGRN_RAT FCGRN_RAT]] Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids (By similarity). [[http://www.uniprot.org/uniprot/B2MG_RAT B2MG_RAT]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 02:01, 25 December 2014

CRYSTAL STRUCTURE OF THE COMPLEX OF RAT NEONATAL FC RECEPTOR WITH FC

1frt, resolution 4.50Å

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