3cvf
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cvf RCSB], [http://www.ebi.ac.uk/pdbsum/3cvf PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cvf RCSB], [http://www.ebi.ac.uk/pdbsum/3cvf PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HOME3_HUMAN HOME3_HUMAN]] Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Giannini, V | + | [[Category: Giannini, V]] |
| - | [[Category: Hayashi, M K | + | [[Category: Hayashi, M K]] |
| - | [[Category: Hayashi, Y | + | [[Category: Hayashi, Y]] |
| - | [[Category: Sala, C | + | [[Category: Sala, C]] |
| - | [[Category: Stearns, M H | + | [[Category: Stearns, M H]] |
| - | [[Category: Xu, R M | + | [[Category: Xu, R M]] |
[[Category: Cell junction]] | [[Category: Cell junction]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
Revision as of 02:16, 25 December 2014
Crystal Structure of the carboxy terminus of Homer3
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