2kg4
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2kg4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KG4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2kg4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KG4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GADD45A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GADD45A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kg4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kg4 RCSB], [http://www.ebi.ac.uk/pdbsum/2kg4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kg4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kg4 RCSB], [http://www.ebi.ac.uk/pdbsum/2kg4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GA45A_HUMAN GA45A_HUMAN]] In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Blanco, F J | + | [[Category: Blanco, F J]] |
| - | [[Category: Campos-Olivas, R | + | [[Category: Campos-Olivas, R]] |
| - | [[Category: Diercks, T | + | [[Category: Diercks, T]] |
| - | [[Category: Pantoja-Uceda, D | + | [[Category: Pantoja-Uceda, D]] |
| - | [[Category: Prieto, J | + | [[Category: Prieto, J]] |
| - | [[Category: Sanchez, R | + | [[Category: Sanchez, R]] |
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Dna damage]] | [[Category: Dna damage]] | ||
Revision as of 02:16, 25 December 2014
Three-dimensional structure of human Gadd45alpha in solution by NMR
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