4tpp

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tpp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tpp RCSB], [http://www.ebi.ac.uk/pdbsum/4tpp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tpp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tpp RCSB], [http://www.ebi.ac.uk/pdbsum/4tpp PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 02:19, 25 December 2014

2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors

4tpp, resolution 2.65Å

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