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4v1c

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v1c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v1c RCSB], [http://www.ebi.ac.uk/pdbsum/4v1c PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v1c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v1c RCSB], [http://www.ebi.ac.uk/pdbsum/4v1c PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SIR3_HUMAN SIR3_HUMAN]] NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.<ref>PMID:16788062</ref> <ref>PMID:18680753</ref> <ref>PMID:18794531</ref> <ref>PMID:19535340</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 02:23, 25 December 2014

sirtuin 3

4v1c, resolution 2.95Å

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