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4lhv
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lhv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lhv RCSB], [http://www.ebi.ac.uk/pdbsum/4lhv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lhv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lhv RCSB], [http://www.ebi.ac.uk/pdbsum/4lhv PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RAB8A_HUMAN RAB8A_HUMAN]] May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.<ref>PMID:20890297</ref> <ref>PMID:21282656</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 02:25, 25 December 2014
Crystal structure of Rab8 in its inactive GDP-bound form
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Categories: Human | Goody, R S | Guo, Z | Hou, X M | Itzen, A | Protein transport | Small gtpase
