4g2b
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g2b RCSB], [http://www.ebi.ac.uk/pdbsum/4g2b PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g2b RCSB], [http://www.ebi.ac.uk/pdbsum/4g2b PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SSEI_SALTY SSEI_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required to maintain a long-term chronic systemic infection in mice. It inhibits normal cell migration of primary macrophages and dendritic cells, by a mechanism that involves interaction with the host factor IQGAP1, an important regulator of the cytoskeleton and cell migration. Also accelerates the systemic spread of infection from the gastrointestinal tract to the bloodstream, probably by interacting with host TRIP6.<ref>PMID:17095609</ref> <ref>PMID:19956712</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 02:28, 25 December 2014
Structure of the Catalytic Domain of the Salmonella Virulence Factor SseI
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