4baf
From Proteopedia
(Difference between revisions)
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| - | + | ==Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution.== | |
| - | + | <StructureSection load='4baf' size='340' side='right' caption='[[4baf]], [[Resolution|resolution]] 1.51Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4baf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BAF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BAF FirstGlance]. <br> | |
| - | ==Function== | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EU3:EUROPIUM+(III)+ION'>EU3</scene>, <scene name='pdbligand=IKX:4-(4-(2-HYDROXYETHYL)-1H-1,2,3-TRIAZOL-1-YL)PYRIDINE-2,6-DICARBOXYLIC+ACID'>IKX</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zvq|3zvq]], [[4a7d|4a7d]], [[4a8a|4a8a]], [[4a8b|4a8b]], [[4aga|4aga]], [[4axt|4axt]], [[4b0d|4b0d]], [[4b1a|4b1a]], [[4b49|4b49]], [[4b4e|4b4e]], [[4b4i|4b4i]], [[4b4j|4b4j]], [[4bad|4bad]]</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4baf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4baf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4baf RCSB], [http://www.ebi.ac.uk/pdbsum/4baf PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | New trisdipicolinic acid-lanthanide complexes are reported as phasing agents for X-ray crystallography of proteins. It is demonstrated that CuAAC modifications allow protein co-crystallization with low concentration of lanthanide complexes leading to an accurate structure determination. | ||
| + | |||
| + | Clicked europium dipicolinate complexes for protein X-ray structure determination.,Talon R, Nauton L, Canet JL, Kahn R, Girard E, Gautier A Chem Commun (Camb). 2012 Nov 12;48(97):11886-8. doi: 10.1039/c2cc36982f. PMID:23123834<ref>PMID:23123834</ref> | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | == | + | ==See Also== |
| - | + | *[[Lysozyme 3D structures|Lysozyme 3D structures]] | |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chick]] | ||
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
| - | [[Category: Gautier, A | + | [[Category: Gautier, A]] |
| - | [[Category: Girard, E | + | [[Category: Girard, E]] |
| - | [[Category: Kahn, R | + | [[Category: Kahn, R]] |
| - | [[Category: Nauton, L | + | [[Category: Nauton, L]] |
| - | [[Category: Talon, R | + | [[Category: Talon, R]] |
[[Category: Anomalous scattering]] | [[Category: Anomalous scattering]] | ||
[[Category: Click-chemistry]] | [[Category: Click-chemistry]] | ||
Revision as of 02:32, 25 December 2014
Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution.
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