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3cey
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3cey]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CEY FirstGlance]. <br> | <table><tr><td colspan='2'>[[3cey]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CEY FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L3MBTL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L3MBTL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cey OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cey RCSB], [http://www.ebi.ac.uk/pdbsum/3cey PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cey OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cey RCSB], [http://www.ebi.ac.uk/pdbsum/3cey PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LMBL2_HUMAN LMBL2_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.<ref>PMID:19233876</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Allali-Hassani, A | + | [[Category: Allali-Hassani, A]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Crombet, L | + | [[Category: Crombet, L]] |
| - | [[Category: Dong, A | + | [[Category: Dong, A]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Guo, Y | + | [[Category: Guo, Y]] |
| - | [[Category: Kozieradzki, I | + | [[Category: Kozieradzki, I]] |
| - | [[Category: Loppnau, P | + | [[Category: Loppnau, P]] |
| - | [[Category: Mackenzie, F | + | [[Category: Mackenzie, F]] |
| - | [[Category: Min, J | + | [[Category: Min, J]] |
| - | [[Category: Nady, N | + | [[Category: Nady, N]] |
| - | [[Category: Pan, P | + | [[Category: Pan, P]] |
| - | [[Category: Qi, C | + | [[Category: Qi, C]] |
| - | [[Category: Read, R | + | [[Category: Read, R]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Vedadi, M | + | [[Category: Vedadi, M]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Zhu, H | + | [[Category: Zhu, H]] |
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
[[Category: Mbt]] | [[Category: Mbt]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Transcription regulator]] | [[Category: Transcription regulator]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 02:33, 25 December 2014
Crystal structure of L3MBTL2
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Categories: Homo sapiens | Allali-Hassani, A | Arrowsmith, C H | Bochkarev, A | Bountra, C | Crombet, L | Dong, A | Edwards, A M | Guo, Y | Kozieradzki, I | Loppnau, P | Mackenzie, F | Min, J | Nady, N | Pan, P | Qi, C | Read, R | Structural genomic | Vedadi, M | Weigelt, J | Zhu, H | Chromatin regulator | Mbt | Metal-binding | Nucleus | Sgc | Transcription | Transcription regulation | Transcription regulator | Zinc-finger
