This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4wqn
From Proteopedia
(Difference between revisions)
| Line 6: | Line 6: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wqn RCSB], [http://www.ebi.ac.uk/pdbsum/4wqn PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wqn RCSB], [http://www.ebi.ac.uk/pdbsum/4wqn PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 02:33, 25 December 2014
Crystal structure of N6-methyladenosine RNA reader YTHDF2
| |||||||||||
Categories: He, C | Li, J | Roundtree, I A | Sun, C | Tian, Y | Wang, L | Wang, P | Wang, X | Xu, Y | Zhu, T | N6-methyladenosine rna reader | Rna binding protein
