3ix6

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ix6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brucella_melitensis Brucella melitensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IX6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ix6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brucella_melitensis Brucella melitensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IX6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thyA, BMEI0608 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29459 Brucella melitensis])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thyA, BMEI0608 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29459 Brucella melitensis])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ix6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ix6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ix6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ix6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ix6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ix6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ix6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ix6 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TYSY_BRUME TYSY_BRUME]] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Brucella melitensis]]
[[Category: Brucella melitensis]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
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[[Category: Structural genomic]]
[[Category: Brucellosis]]
[[Category: Brucellosis]]
[[Category: Epididymitis]]
[[Category: Epididymitis]]
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[[Category: Orchitis]]
[[Category: Orchitis]]
[[Category: Seattle structural center for infectious disease]]
[[Category: Seattle structural center for infectious disease]]
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[[Category: Seattle structural genomics center for infectious disease]]
 
[[Category: Ssgcid]]
[[Category: Ssgcid]]
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[[Category: Structural genomic]]
 
[[Category: Thymidylate]]
[[Category: Thymidylate]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 02:36, 25 December 2014

Crystal structure of Thymidylate synthase thyA from Brucella melitensis

3ix6, resolution 2.20Å

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