3a1g

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a1g RCSB], [http://www.ebi.ac.uk/pdbsum/3a1g PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a1g RCSB], [http://www.ebi.ac.uk/pdbsum/3a1g PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/RDRP_I34A1 RDRP_I34A1]] RNA-dependent RNA polymerase which is responsible for replication and transcription of virus segments. Binds the promoter sequence of the encapsidated viral RNA. Displays an endonuclease activity involved in cap-stealing. Cleaves cellular pre-mRNA to generate primers for viral transcription. [[http://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==See Also==
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*[[RNA polymerase|RNA polymerase]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: Obayashi, E.]]
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[[Category: Obayashi, E]]
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[[Category: Park, S Y.]]
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[[Category: Park, S Y]]
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[[Category: Sugiyama, K.]]
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[[Category: Sugiyama, K]]
[[Category: Influenza virus]]
[[Category: Influenza virus]]
[[Category: Mitochondrion]]
[[Category: Mitochondrion]]

Revision as of 02:44, 25 December 2014

High-Resolution Crystal Structure of RNA polymerase PB1-PB2 subunits from Influenza A Virus

3a1g, resolution 1.70Å

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