3b4t

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3b4t]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B4T FirstGlance]. <br>
<table><tr><td colspan='2'>[[3b4t]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B4T FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rph, rphA, Rv1340, MT1381, MTCY130.25, MTCY02B10.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rph, rphA, Rv1340, MT1381, MTCY130.25, MTCY02B10.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_nucleotidyltransferase tRNA nucleotidyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.56 2.7.7.56] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_nucleotidyltransferase tRNA nucleotidyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.56 2.7.7.56] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b4t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b4t RCSB], [http://www.ebi.ac.uk/pdbsum/3b4t PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b4t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b4t RCSB], [http://www.ebi.ac.uk/pdbsum/3b4t PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RNPH_MYCTU RNPH_MYCTU]] Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease|Ribonuclease]]
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*[[Temp|Temp]]
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*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: TRNA nucleotidyltransferase]]
[[Category: TRNA nucleotidyltransferase]]
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[[Category: Antczak, A J.]]
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[[Category: Antczak, A J]]
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[[Category: Berger, J M.]]
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[[Category: Berger, J M]]
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[[Category: Lekin, T.]]
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[[Category: Lekin, T]]
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[[Category: Segelke, B W.]]
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[[Category: Segelke, B W]]
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[[Category: TBSGC, Mycobacterium Tuberculosis Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Mycobacterium tuberculosis structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Ribonuclease]]
[[Category: Ribonuclease]]
[[Category: Rnase]]
[[Category: Rnase]]
[[Category: Rpha]]
[[Category: Rpha]]
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[[Category: Structural genomic]]
 
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[[Category: Tb structural genomics consortium]]
 
[[Category: Tbsgc]]
[[Category: Tbsgc]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Trna nucleotidyltransferase]]
[[Category: Trna nucleotidyltransferase]]
[[Category: Trna processing]]
[[Category: Trna processing]]

Revision as of 02:45, 25 December 2014

Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340

3b4t, resolution 2.10Å

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