1uhp
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1uhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UHP FirstGlance]. <br> | <table><tr><td colspan='2'>[[1uhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UHP FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA1095 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA1095 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uhp RCSB], [http://www.ebi.ac.uk/pdbsum/1uhp PDBsum], [http://www.topsan.org/Proteins/RSGI/1uhp TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uhp RCSB], [http://www.ebi.ac.uk/pdbsum/1uhp PDBsum], [http://www.topsan.org/Proteins/RSGI/1uhp TOPSAN]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/PZRN3_HUMAN PZRN3_HUMAN]] E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Hamada, T | + | [[Category: Hamada, T]] |
- | [[Category: Hirota, H | + | [[Category: Hirota, H]] |
- | [[Category: Muto, Y | + | [[Category: Muto, Y]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Pdz domain]] | [[Category: Pdz domain]] | ||
- | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Semaphorin cytoplasmic domain associated protein]] | [[Category: Semaphorin cytoplasmic domain associated protein]] | ||
- | [[Category: Structural genomic]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] |
Revision as of 02:45, 25 December 2014
Solution structure of RSGI RUH-005, a PDZ domain in human cDNA, KIAA1095
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