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2kg0

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kg0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KG0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kg0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KG0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hgm|2hgm]], [[2kfy|2kfy]], [[2kg1|2kg1]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hgm|2hgm]], [[2kfy|2kfy]], [[2kg1|2kg1]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2kg0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2kg0 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/HNRPF_HUMAN HNRPF_HUMAN]] Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.<ref>PMID:20526337</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Allain, F H.T.]]
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[[Category: Allain, F H.T]]
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[[Category: Dominguez, C.]]
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[[Category: Dominguez, C]]
[[Category: G tract]]
[[Category: G tract]]
[[Category: Mrna processing]]
[[Category: Mrna processing]]

Revision as of 02:49, 25 December 2014

Structure of the second qRRM domain of hnRNP F in complex with a AGGGAU G-tract RNA

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