2wgp

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wgp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WGP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wgp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WGP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wgp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wgp RCSB], [http://www.ebi.ac.uk/pdbsum/2wgp PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wgp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wgp RCSB], [http://www.ebi.ac.uk/pdbsum/2wgp PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DUS14_HUMAN DUS14_HUMAN]] Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cherry, S.]]
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[[Category: Cherry, S]]
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[[Category: Lountos, G T.]]
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[[Category: Lountos, G T]]
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[[Category: Tropea, J E.]]
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[[Category: Tropea, J E]]
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[[Category: Waugh, D S.]]
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[[Category: Waugh, D S]]
[[Category: Dual specificity phosphatase]]
[[Category: Dual specificity phosphatase]]
[[Category: Dusp14]]
[[Category: Dusp14]]

Revision as of 02:50, 25 December 2014

CRYSTAL STRUCTURE OF HUMAN DUAL SPECIFICITY PHOSPHATASE 14

2wgp, resolution 1.88Å

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