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2k50
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2k50]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K50 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K50 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2k50]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K50 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K50 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTH1385, MTH_1385 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 Methanothermobacter thermautotrophicus str. Delta H])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTH1385, MTH_1385 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 Methanothermobacter thermautotrophicus str. Delta H])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k50 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k50 RCSB], [http://www.ebi.ac.uk/pdbsum/2k50 PDBsum], [http://www.topsan.org/Proteins/NESGC/2k50 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k50 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k50 RCSB], [http://www.ebi.ac.uk/pdbsum/2k50 PDBsum], [http://www.topsan.org/Proteins/NESGC/2k50 TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/O27438_METTH O27438_METTH]] Inhibits DNA polymerase activity of PolB, which can be overcome by RFC and PNCA. Stimulates 3'-to 5'-exonuclease activity of PolB at 30 degrees Celsius, but has no effect at 50 or 70 degrees Celsius. Bind ssDNA and replication forks; replication forks structures bind both Hel308 and this protein. Has no effect on helicase activity of Hel308; may help target the helicase to DNA substrates that require DNA re-modeling.<ref>PMID:10497247</ref> <ref>PMID:21195035</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Methanothermobacter thermautotrophicus str. delta h]] | [[Category: Methanothermobacter thermautotrophicus str. delta h]] | ||
| - | [[Category: Acton, T B | + | [[Category: Acton, T B]] |
| - | [[Category: Ciccosanti, C | + | [[Category: Ciccosanti, C]] |
| - | [[Category: Everett, J K | + | [[Category: Everett, J K]] |
| - | [[Category: Foote, E L | + | [[Category: Foote, E L]] |
| - | [[Category: Jiang, M | + | [[Category: Jiang, M]] |
| - | [[Category: Maglaqui, M | + | [[Category: Maglaqui, M]] |
| - | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
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[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
| + | [[Category: Nair, R]] | ||
| + | [[Category: Rossi, P]] | ||
| + | [[Category: Rost, B]] | ||
| + | [[Category: Swapna, G]] | ||
| + | [[Category: Xiao, R]] | ||
| + | [[Category: Nesg]] | ||
| + | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Uncharacterized protein]] | [[Category: Uncharacterized protein]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 02:58, 25 December 2014
Solution NMR Structure of the replication Factor A Related Protein from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Target TR91A.
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Categories: Methanothermobacter thermautotrophicus str. delta h | Acton, T B | Ciccosanti, C | Everett, J K | Foote, E L | Jiang, M | Maglaqui, M | Montelione, G T | Structural genomic | Nair, R | Rossi, P | Rost, B | Swapna, G | Xiao, R | Nesg | PSI, Protein structure initiative | Uncharacterized protein | Unknown function
