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2e9c
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2e9c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E9C FirstGlance]. <br> | <table><tr><td colspan='2'>[[2e9c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E9C FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B75:1-HYDROXY-2-[3-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC+ACID'>B75</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B75:1-HYDROXY-2-[3-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC+ACID'>B75</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x06|1x06]], [[1x07|1x07]], [[1x08|1x08]], [[1x09|1x09]], [[2e98|2e98]], [[2e99|2e99]], [[2e9a|2e9a]], [[2e9d|2e9d]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x06|1x06]], [[1x07|1x07]], [[1x08|1x08]], [[1x09|1x09]], [[2e98|2e98]], [[2e99|2e99]], [[2e9a|2e9a]], [[2e9d|2e9d]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Di-trans,poly-cis-decaprenylcistransferase Di-trans,poly-cis-decaprenylcistransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Di-trans,poly-cis-decaprenylcistransferase Di-trans,poly-cis-decaprenylcistransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e9c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e9c RCSB], [http://www.ebi.ac.uk/pdbsum/2e9c PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e9c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e9c RCSB], [http://www.ebi.ac.uk/pdbsum/2e9c PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI]] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Di-trans,poly-cis-decaprenylcistransferase]] | [[Category: Di-trans,poly-cis-decaprenylcistransferase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Cao, R | + | [[Category: Cao, R]] |
| - | [[Category: Guo, R T | + | [[Category: Guo, R T]] |
| - | [[Category: Ko, T P | + | [[Category: Ko, T P]] |
| - | [[Category: Liang, P H | + | [[Category: Liang, P H]] |
| - | [[Category: Oldfield, E | + | [[Category: Oldfield, E]] |
| - | [[Category: Wang, A H.J | + | [[Category: Wang, A H.J]] |
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
[[Category: Bisphosphonate]] | [[Category: Bisphosphonate]] | ||
Revision as of 03:00, 25 December 2014
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675
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