2lks

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<StructureSection load='2lks' size='340' side='right' caption='[[2lks]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2lks' size='340' side='right' caption='[[2lks]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lks]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LKS OCA]. <br>
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<table><tr><td colspan='2'>[[2lks]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LKS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LKS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kzg|2kzg]], [[1uzc|1uzc]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kzg|2kzg]], [[1uzc|1uzc]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FBP11, FLAF1, FNBP3, HIP10, HSPC225, HYPA, Hypa/FBP11, PRPF40A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FBP11, FLAF1, FNBP3, HIP10, HSPC225, HYPA, Hypa/FBP11, PRPF40A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lks OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lks RCSB], [http://www.ebi.ac.uk/pdbsum/2lks PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lks OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lks RCSB], [http://www.ebi.ac.uk/pdbsum/2lks PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN]] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta.,Barette J, Velyvis A, Religa TL, Korzhnev DM, Kay LE J Phys Chem B. 2011 Dec 23. PMID:22148426<ref>PMID:22148426</ref>
Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta.,Barette J, Velyvis A, Religa TL, Korzhnev DM, Kay LE J Phys Chem B. 2011 Dec 23. PMID:22148426<ref>PMID:22148426</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Barette, J.]]
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[[Category: Barette, J]]
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[[Category: Kay, L E.]]
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[[Category: Kay, L E]]
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[[Category: Korzhnev, D M.]]
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[[Category: Korzhnev, D M]]
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[[Category: Religa, T L.]]
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[[Category: Religa, T L]]
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[[Category: Velyvis, A.]]
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[[Category: Velyvis, A]]
[[Category: Protein binding]]
[[Category: Protein binding]]

Revision as of 03:08, 25 December 2014

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