4u0m
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u0m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u0m RCSB], [http://www.ebi.ac.uk/pdbsum/4u0m PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u0m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u0m RCSB], [http://www.ebi.ac.uk/pdbsum/4u0m PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DNCV_VIBCH DNCV_VIBCH]] Catalyzes the synthesis of cyclic AMP-GMP from ATP and GTP. Is also able to produce c-di-AMP and c-di-GMP from ATP and GTP, respectively; however, c-AMP-GMP is the dominant molecule produced by DncV in vivo. Is required for efficient V.cholerae intestinal colonization, and down-regulates the colonization-influencing process of chemotaxis. Is not active with dATP, TTP, UTP, and CTP. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cyclic GMP-AMP synthase]] | [[Category: Cyclic GMP-AMP synthase]] | ||
| - | [[Category: Xiang, Y | + | [[Category: Xiang, Y]] |
| - | [[Category: Zhu, D | + | [[Category: Zhu, D]] |
[[Category: Mutation]] | [[Category: Mutation]] | ||
[[Category: Regulation]] | [[Category: Regulation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 03:18, 25 December 2014
Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) mutant D193N in complex with ATP, GTP and 5MTHFGLU2
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