2b8o
From Proteopedia
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- | [[Image:2b8o.gif|left|200px]] | + | [[Image:2b8o.gif|left|200px]] |
- | + | ||
- | '''Crystal Structure of Glu-Gly-Arg-Chloromethyl Ketone-Factor VIIa/Soluble Tissue Factor Complex''' | + | {{Structure |
+ | |PDB= 2b8o |SIZE=350|CAPTION= <scene name='initialview01'>2b8o</scene>, resolution 2.8Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene> | ||
+ | |ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21] | ||
+ | |GENE= F7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), F3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
+ | }} | ||
+ | |||
+ | '''Crystal Structure of Glu-Gly-Arg-Chloromethyl Ketone-Factor VIIa/Soluble Tissue Factor Complex''' | ||
+ | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
- | 2B8O is a [ | + | 2B8O is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B8O OCA]. |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: zinc]] | [[Category: zinc]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:58:51 2008'' |
Revision as of 13:58, 20 March 2008
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, resolution 2.8Å | |||||||
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Ligands: | , , , , , and | ||||||
Gene: | F7 (Homo sapiens), F3 (Homo sapiens) | ||||||
Activity: | Coagulation factor VIIa, with EC number 3.4.21.21 | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Crystal Structure of Glu-Gly-Arg-Chloromethyl Ketone-Factor VIIa/Soluble Tissue Factor Complex
Disease
Known diseases associated with this structure: Esophageal squamous cell carcinoma OMIM:[606551], Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
2B8O is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 15:58:51 2008
Categories: Coagulation factor VIIa | Homo sapiens | Protein complex | Bajaj, S P. | Padmanabhan, K. | Schmidt, A E. | CA | CL | FUC | GLC | MG | NA | ZN | Blood | Blood coagualtion | Calcium | Clotting | Clotting factor | Coagulation | Coagulation factor | Egr | Factor viia | Glu-gly-arg chloromethylketone | Magnesium | Serine protease | Sodium | Tissue factor | Zinc