1ux4
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ux4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UX4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ux4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UX4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ux5|1ux5]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ux5|1ux5]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ux4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ux4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ux4 RCSB], [http://www.ebi.ac.uk/pdbsum/1ux4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ux4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ux4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ux4 RCSB], [http://www.ebi.ac.uk/pdbsum/1ux4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BNI1_YEAST BNI1_YEAST]] Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and acts as leaky capper, slowing both polymerization and depolymerization. Protects the growing actin fiber from tight capping proteins and so increases the time of elongation and the total amount of F-actin. May organize microtubules by mediating spindle positioning and movement in the budding process. Potential target of the RHO family members.<ref>PMID:10085293</ref> <ref>PMID:14561409</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Eck, M J | + | [[Category: Eck, M J]] |
| - | [[Category: Goode, B L | + | [[Category: Goode, B L]] |
| - | [[Category: Moseley, J B | + | [[Category: Moseley, J B]] |
| - | [[Category: Pellman, D | + | [[Category: Pellman, D]] |
| - | [[Category: Poy, F | + | [[Category: Poy, F]] |
| - | [[Category: Sagot, I | + | [[Category: Sagot, I]] |
| - | [[Category: Xu, Y | + | [[Category: Xu, Y]] |
[[Category: Fh2 actin cytoskeleton]] | [[Category: Fh2 actin cytoskeleton]] | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
Revision as of 03:22, 25 December 2014
CRYSTAL STRUCTURES OF A FORMIN HOMOLOGY-2 DOMAIN REVEAL A TETHERED-DIMER ARCHITECTURE
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