4emv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4emv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_ga47373 Streptococcus pneumoniae ga47373]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EMV FirstGlance]. <br> | <table><tr><td colspan='2'>[[4emv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_ga47373 Streptococcus pneumoniae ga47373]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EMV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0R9:5-{2-(ETHYLCARBAMOYL)-4-[3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1H-PYRROLO[2,3-B]PYRIDIN-5-YL}PYRIDINE-3-CARBOXYLIC+ACID'>0R9</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0R9:5-{2-(ETHYLCARBAMOYL)-4-[3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1H-PYRROLO[2,3-B]PYRIDIN-5-YL}PYRIDINE-3-CARBOXYLIC+ACID'>0R9</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4em7|4em7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4em7|4em7]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ParE, SPAR94_0831 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=760835 Streptococcus pneumoniae GA47373])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ParE, SPAR94_0831 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=760835 Streptococcus pneumoniae GA47373])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4emv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4emv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4emv RCSB], [http://www.ebi.ac.uk/pdbsum/4emv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4emv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4emv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4emv RCSB], [http://www.ebi.ac.uk/pdbsum/4emv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/G6TGY9_STRPN G6TGY9_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule (By similarity).[HAMAP-Rule:MF_00939] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptococcus pneumoniae ga47373]] | [[Category: Streptococcus pneumoniae ga47373]] | ||
| - | [[Category: Boriack-Sjodin, P A | + | [[Category: Boriack-Sjodin, P A]] |
| - | [[Category: Hull, K | + | [[Category: Hull, K]] |
| - | [[Category: Manchester, J | + | [[Category: Manchester, J]] |
[[Category: Antimicrobial]] | [[Category: Antimicrobial]] | ||
[[Category: Atp binding]] | [[Category: Atp binding]] | ||
Revision as of 03:26, 25 December 2014
Crystal structure of a topoisomerase ATP inhibitor
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