4ii4

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ii4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4II4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4II4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ii4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4II4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4II4 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BYC:BENZOYL+COENZYME+A'>BYC</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BYC:BENZOYL+COENZYME+A'>BYC</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pvr|3pvr]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pvr|3pvr]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylacetyl-CoA_1,2-epoxidase Phenylacetyl-CoA 1,2-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.149 1.14.13.149] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylacetyl-CoA_1,2-epoxidase Phenylacetyl-CoA 1,2-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.149 1.14.13.149] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ii4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ii4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ii4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ii4 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ii4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ii4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ii4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ii4 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PAAA_ECOLI PAAA_ECOLI]] Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA. The subunit A is the catalytic subunit involved in the incorporation of one atom of molecular oxygen into phenylacetyl-CoA.<ref>PMID:9748275</ref> <ref>PMID:16997993</ref> <ref>PMID:20660314</ref> <ref>PMID:21247899</ref> [[http://www.uniprot.org/uniprot/PAAC_ECOLI PAAC_ECOLI]] Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA. The subunit C may be essential for structural integrity of the alpha subunit.<ref>PMID:9748275</ref> <ref>PMID:16997993</ref> <ref>PMID:20660314</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Phenylacetyl-CoA 1,2-epoxidase]]
[[Category: Phenylacetyl-CoA 1,2-epoxidase]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Cygler, M.]]
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[[Category: Cygler, M]]
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[[Category: Grishin, A M.]]
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[[Category: Grishin, A M]]
[[Category: Bacterial multicomponent monooxygenase paaabce]]
[[Category: Bacterial multicomponent monooxygenase paaabce]]
[[Category: Bsgi]]
[[Category: Bsgi]]
[[Category: Ferritin-like fold]]
[[Category: Ferritin-like fold]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
 
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]
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[[Category: Structural genomic]]
 

Revision as of 03:27, 25 December 2014

The Phenylacetyl-CoA monooxygenase - mutant PaaA E49Q K68Q - PaaC wild type subcomplex with benzoyl-CoA

4ii4, resolution 2.80Å

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