1ej6
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ej6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ej6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ej6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ej6 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ej6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ej6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ej6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ej6 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LMBD2_REOVD LMBD2_REOVD]] Outer capsid protein involved in mRNA capping. Catalyzes the last 3 enzymatic activities for formation of the 5' cap structure on the viral plus-strand transcripts, namely the RNA guanylyltransferase, RNA-7N- and RNA-2'O-methyltransferase activities. [[http://www.uniprot.org/uniprot/SIGM2_REOVD SIGM2_REOVD]] Inner capsid (core) component. [[http://www.uniprot.org/uniprot/LMBD1_REOVD LMBD1_REOVD]] Inner capsid (core) component. Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome. Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis. RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 03:28, 25 December 2014
Reovirus core
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