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2bel
From Proteopedia
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| - | [[Image:2bel.gif|left|200px]] | + | [[Image:2bel.gif|left|200px]] |
| - | + | ||
| - | '''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE''' | + | {{Structure |
| + | |PDB= 2bel |SIZE=350|CAPTION= <scene name='initialview01'>2bel</scene>, resolution 2.11Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+C'>AC1</scene> | ||
| + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE''' | ||
| + | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2BEL is a [ | + | 2BEL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BEL OCA]. |
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: steroid metabolism]] | [[Category: steroid metabolism]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:00:56 2008'' |
Revision as of 14:00, 20 March 2008
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| , resolution 2.11Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , and | ||||||
| Activity: | 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE
Disease
Known diseases associated with this structure: Cortisone reductase deficiency OMIM:[600713]
About this Structure
2BEL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 16:00:56 2008
Categories: 11-beta-hydroxysteroid dehydrogenase | Homo sapiens | Single protein | Abrahmsen, L. | Arrowsmith, C. | Bray, J. | Debreczeni, J E. | Delft, F Von. | Edwards, A. | Elleby, B. | Kavanagh, K. | Oppermann, U. | Sharma, S. | Sundstrom, M. | Svensson, S. | Wu, X. | CBO | CL | NAP | Drug target | Glucocorticoid activation | Hormone metabolism | Inhibitor | Microsome | Nadp | Oxidoreductase | Short-chain dehydrogenase/reductase | Steroid metabolism
