3cz6
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz6 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz6 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz6 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz6 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RAP1_YEAST RAP1_YEAST]] Essential regulatory protein in yeast whose DNA-binding sites are found at three types of chromosomal elements: promoters, silencers, and telomeres. RAP1 is also involved in the regulation of telomere structure, where its binding sites are found within the terminal poly[C(1-3)A] sequences. The opposite regulatory functions of RAP1 are not intrinsic to its binding sites but, instead, result from interactions with different factors at promoters and silencers. RAP1 associates with SIR3 and SIR4 proteins to form a DNA-binding complex that initiates the repression at the HM loci and telomeres. May also target the binding of RIF1 and RIF2 to silencers and telomeres. Forms with GCR1 a transcriptional activation complex that is required for expression of glycolytic and ribosomal gene. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Feeser, E A | + | [[Category: Feeser, E A]] |
| - | [[Category: Wolberger, C | + | [[Category: Wolberger, C]] |
[[Category: Activator]] | [[Category: Activator]] | ||
[[Category: Chromosomal protein]] | [[Category: Chromosomal protein]] | ||
Revision as of 04:05, 25 December 2014
Crystal Structure of the Rap1 C-terminus
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