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2v2w

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2v2w]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2bsu 2bsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V2W FirstGlance]. <br>
<table><tr><td colspan='2'>[[2v2w]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2bsu 2bsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V2W FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1akj|1akj]], [[1ao7|1ao7]], [[1aqd|1aqd]], [[1b0g|1b0g]], [[1b0r|1b0r]], [[1bd2|1bd2]], [[1duy|1duy]], [[1duz|1duz]], [[1eey|1eey]], [[1eez|1eez]], [[1hhg|1hhg]], [[1hhh|1hhh]], [[1hhi|1hhi]], [[1hhj|1hhj]], [[1hhk|1hhk]], [[1hla|1hla]], [[1i1f|1i1f]], [[1i1y|1i1y]], [[1i4f|1i4f]], [[1i7r|1i7r]], [[1i7t|1i7t]], [[1i7u|1i7u]], [[1im3|1im3]], [[1jf1|1jf1]], [[1jht|1jht]], [[1lp9|1lp9]], [[1oga|1oga]], [[1p7q|1p7q]], [[1qew|1qew]], [[1qr1|1qr1]], [[1qrn|1qrn]], [[1qse|1qse]], [[1qsf|1qsf]], [[1s8d|1s8d]], [[1s9w|1s9w]], [[1s9x|1s9x]], [[1s9y|1s9y]], [[1t1w|1t1w]], [[1t1x|1t1x]], [[1t1y|1t1y]], [[1t1z|1t1z]], [[1t20|1t20]], [[1t21|1t21]], [[1t22|1t22]], [[1tvb|1tvb]], [[1tvh|1tvh]], [[1ur7|1ur7]], [[2av1|2av1]], [[2av7|2av7]], [[2bnq|2bnq]], [[2bnr|2bnr]], [[2bsu|2bsu]], [[2bsv|2bsv]], [[2c7u|2c7u]], [[2clr|2clr]], [[2gj6|2gj6]], [[2jcc|2jcc]], [[2uwe|2uwe]], [[3hla|3hla]], [[1a1m|1a1m]], [[1a1n|1a1n]], [[1a1o|1a1o]], [[1a6z|1a6z]], [[1a9b|1a9b]], [[1a9e|1a9e]], [[1agb|1agb]], [[1agc|1agc]], [[1agd|1agd]], [[1age|1age]], [[1agf|1agf]], [[1c16|1c16]], [[1ce6|1ce6]], [[1cg9|1cg9]], [[1de4|1de4]], [[1e27|1e27]], [[1e28|1e28]], [[1efx|1efx]], [[1exu|1exu]], [[1gzp|1gzp]], [[1gzq|1gzq]], [[1hsa|1hsa]], [[1hsb|1hsb]], [[1im9|1im9]], [[1jgd|1jgd]], [[1jge|1jge]], [[1jnj|1jnj]], [[1k5n|1k5n]], [[1kpr|1kpr]], [[1ktl|1ktl]], [[1lds|1lds]], [[1m05|1m05]], [[1m6o|1m6o]], [[1mhe|1mhe]], [[1mi5|1mi5]], [[1n2r|1n2r]], [[1of2|1of2]], [[1ogt|1ogt]], [[1onq|1onq]], [[1py4|1py4]], [[1q94|1q94]], [[1qlf|1qlf]], [[1qqd|1qqd]], [[1qvo|1qvo]], [[1r3h|1r3h]], [[1sys|1sys]], [[1syv|1syv]], [[1tmc|1tmc]], [[1uqs|1uqs]], [[1uxs|1uxs]], [[1uxw|1uxw]], [[1vgk|1vgk]], [[1w0v|1w0v]], [[1w0w|1w0w]], [[1w72|1w72]], [[1x7q|1x7q]], [[1xh3|1xh3]], [[1xr8|1xr8]], [[1xr9|1xr9]], [[1xz0|1xz0]], [[1ydp|1ydp]], [[1ypz|1ypz]], [[1zs8|1zs8]], [[1zsd|1zsd]], [[1zt4|1zt4]], [[2a83|2a83]], [[2ak4|2ak4]], [[2axf|2axf]], [[2axg|2axg]], [[2bck|2bck]], [[2bsr|2bsr]], [[2bss|2bss]], [[2bst|2bst]], [[2bvq|2bvq]], [[2cii|2cii]], [[2cik|2cik]], [[2d31|2d31]], [[2esv|2esv]], [[2f74|2f74]], [[2f8o|2f8o]], [[2h26|2h26]], [[2hjk|2hjk]], [[2hjl|2hjl]], [[2hla|2hla]], [[2v2x|2v2x]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1akj|1akj]], [[1ao7|1ao7]], [[1aqd|1aqd]], [[1b0g|1b0g]], [[1b0r|1b0r]], [[1bd2|1bd2]], [[1duy|1duy]], [[1duz|1duz]], [[1eey|1eey]], [[1eez|1eez]], [[1hhg|1hhg]], [[1hhh|1hhh]], [[1hhi|1hhi]], [[1hhj|1hhj]], [[1hhk|1hhk]], [[1hla|1hla]], [[1i1f|1i1f]], [[1i1y|1i1y]], [[1i4f|1i4f]], [[1i7r|1i7r]], [[1i7t|1i7t]], [[1i7u|1i7u]], [[1im3|1im3]], [[1jf1|1jf1]], [[1jht|1jht]], [[1lp9|1lp9]], [[1oga|1oga]], [[1p7q|1p7q]], [[1qew|1qew]], [[1qr1|1qr1]], [[1qrn|1qrn]], [[1qse|1qse]], [[1qsf|1qsf]], [[1s8d|1s8d]], [[1s9w|1s9w]], [[1s9x|1s9x]], [[1s9y|1s9y]], [[1t1w|1t1w]], [[1t1x|1t1x]], [[1t1y|1t1y]], [[1t1z|1t1z]], [[1t20|1t20]], [[1t21|1t21]], [[1t22|1t22]], [[1tvb|1tvb]], [[1tvh|1tvh]], [[1ur7|1ur7]], [[2av1|2av1]], [[2av7|2av7]], [[2bnq|2bnq]], [[2bnr|2bnr]], [[2bsu|2bsu]], [[2bsv|2bsv]], [[2c7u|2c7u]], [[2clr|2clr]], [[2gj6|2gj6]], [[2jcc|2jcc]], [[2uwe|2uwe]], [[3hla|3hla]], [[1a1m|1a1m]], [[1a1n|1a1n]], [[1a1o|1a1o]], [[1a6z|1a6z]], [[1a9b|1a9b]], [[1a9e|1a9e]], [[1agb|1agb]], [[1agc|1agc]], [[1agd|1agd]], [[1age|1age]], [[1agf|1agf]], [[1c16|1c16]], [[1ce6|1ce6]], [[1cg9|1cg9]], [[1de4|1de4]], [[1e27|1e27]], [[1e28|1e28]], [[1efx|1efx]], [[1exu|1exu]], [[1gzp|1gzp]], [[1gzq|1gzq]], [[1hsa|1hsa]], [[1hsb|1hsb]], [[1im9|1im9]], [[1jgd|1jgd]], [[1jge|1jge]], [[1jnj|1jnj]], [[1k5n|1k5n]], [[1kpr|1kpr]], [[1ktl|1ktl]], [[1lds|1lds]], [[1m05|1m05]], [[1m6o|1m6o]], [[1mhe|1mhe]], [[1mi5|1mi5]], [[1n2r|1n2r]], [[1of2|1of2]], [[1ogt|1ogt]], [[1onq|1onq]], [[1py4|1py4]], [[1q94|1q94]], [[1qlf|1qlf]], [[1qqd|1qqd]], [[1qvo|1qvo]], [[1r3h|1r3h]], [[1sys|1sys]], [[1syv|1syv]], [[1tmc|1tmc]], [[1uqs|1uqs]], [[1uxs|1uxs]], [[1uxw|1uxw]], [[1vgk|1vgk]], [[1w0v|1w0v]], [[1w0w|1w0w]], [[1w72|1w72]], [[1x7q|1x7q]], [[1xh3|1xh3]], [[1xr8|1xr8]], [[1xr9|1xr9]], [[1xz0|1xz0]], [[1ydp|1ydp]], [[1ypz|1ypz]], [[1zs8|1zs8]], [[1zsd|1zsd]], [[1zt4|1zt4]], [[2a83|2a83]], [[2ak4|2ak4]], [[2axf|2axf]], [[2axg|2axg]], [[2bck|2bck]], [[2bsr|2bsr]], [[2bss|2bss]], [[2bst|2bst]], [[2bvq|2bvq]], [[2cii|2cii]], [[2cik|2cik]], [[2d31|2d31]], [[2esv|2esv]], [[2f74|2f74]], [[2f8o|2f8o]], [[2h26|2h26]], [[2hjk|2hjk]], [[2hjl|2hjl]], [[2hla|2hla]], [[2v2x|2v2x]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v2w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v2w RCSB], [http://www.ebi.ac.uk/pdbsum/2v2w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v2w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v2w RCSB], [http://www.ebi.ac.uk/pdbsum/2v2w PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/1A02_HUMAN 1A02_HUMAN]] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dong, T.]]
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[[Category: Dong, T]]
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[[Category: Dorrell, L.]]
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[[Category: Dorrell, L]]
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[[Category: Douek, D C.]]
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[[Category: Douek, D C]]
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[[Category: Gleria, K Di.]]
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[[Category: Gleria, K Di]]
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[[Category: Harlos, K.]]
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[[Category: Harlos, K]]
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[[Category: Jones, E Y.]]
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[[Category: Jones, E Y]]
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[[Category: Lee, J K.]]
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[[Category: Lee, J K]]
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[[Category: Mcmichael, A J.]]
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[[Category: Mcmichael, A J]]
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[[Category: Merwe, P A.Van Der.]]
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[[Category: Merwe, P A.Van Der]]
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[[Category: Stewart-Jones, G.]]
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[[Category: Stewart-Jones, G]]
[[Category: Aid]]
[[Category: Aid]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]

Revision as of 04:09, 25 December 2014

T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT

2v2w, resolution 1.60Å

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