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3kuw
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kuw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kuw RCSB], [http://www.ebi.ac.uk/pdbsum/3kuw PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kuw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kuw RCSB], [http://www.ebi.ac.uk/pdbsum/3kuw PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q1EMV2_STRCT Q1EMV2_STRCT]] Hydrolyzes fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance. Can not use acetyl-CoA as substrate.<ref>PMID:16720268</ref> <ref>PMID:20836570</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 04:19, 25 December 2014
Structural basis of the activity ans substrate specificity of the fluoroacetyl-CoA thioesterase FlK - T42S mutant in complex with Fluoro-acetate
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