2bhh

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[[Image:2bhh.gif|left|200px]]<br /><applet load="2bhh" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2bhh.gif|left|200px]]
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caption="2bhh, resolution 2.6000&Aring;" />
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'''HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE'''<br />
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{{Structure
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|PDB= 2bhh |SIZE=350|CAPTION= <scene name='initialview01'>2bhh</scene>, resolution 2.6000&Aring;
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|SITE= <scene name='pdbsite=AC1:Ryu+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=RYU:(2E,3S)-3-HYDROXY-5'-[(4-HYDROXYPIPERIDIN-1-YL)SULFONYL]-3-METHYL-1,3-DIHYDRO-2,3'-BIINDOL-2'(1'H)-ONE'>RYU</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37]
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|GENE=
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}}
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'''HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE'''
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==About this Structure==
==About this Structure==
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2BHH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=RYU:'>RYU</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37] Known structural/functional Site: <scene name='pdbsite=AC1:Ryu+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BHH OCA].
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2BHH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BHH OCA].
==Reference==
==Reference==
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From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors., Jautelat R, Brumby T, Schafer M, Briem H, Eisenbrand G, Schwahn S, Kruger M, Lucking U, Prien O, Siemeister G, Chembiochem. 2005 Mar;6(3):531-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15742375 15742375]
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From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors., Jautelat R, Brumby T, Schafer M, Briem H, Eisenbrand G, Schwahn S, Kruger M, Lucking U, Prien O, Siemeister G, Chembiochem. 2005 Mar;6(3):531-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15742375 15742375]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:37:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:02:01 2008''

Revision as of 14:02, 20 March 2008

Image:2bhh.gif


PDB ID 2bhh

Drag the structure with the mouse to rotate
, resolution 2.6000Å
Sites:
Ligands:
Activity: Transferred entry: 2.7.11.1, with EC number 2.7.1.37
Coordinates: save as pdb, mmCIF, xml



HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE


About this Structure

2BHH is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors., Jautelat R, Brumby T, Schafer M, Briem H, Eisenbrand G, Schwahn S, Kruger M, Lucking U, Prien O, Siemeister G, Chembiochem. 2005 Mar;6(3):531-40. PMID:15742375

Page seeded by OCA on Thu Mar 20 16:02:01 2008

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