3to8
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3to8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TO8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3to8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TO8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRNPL, HNRPL, P/OKcl.14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRNPL, HNRPL, P/OKcl.14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3to8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3to8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3to8 RCSB], [http://www.ebi.ac.uk/pdbsum/3to8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3to8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3to8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3to8 RCSB], [http://www.ebi.ac.uk/pdbsum/3to8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HNRPL_HUMAN HNRPL_HUMAN]] Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.<ref>PMID:11809897</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Li, X | + | [[Category: Li, X]] |
| - | [[Category: Liu, Y W | + | [[Category: Liu, Y W]] |
| - | [[Category: Niu, L W | + | [[Category: Niu, L W]] |
| - | [[Category: Teng, M K | + | [[Category: Teng, M K]] |
| - | [[Category: Zeng, F X | + | [[Category: Zeng, F X]] |
| - | [[Category: Zhang, W J | + | [[Category: Zhang, W J]] |
| - | [[Category: Zhao, Y | + | [[Category: Zhao, Y]] |
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
[[Category: Rna recognition motif]] | [[Category: Rna recognition motif]] | ||
[[Category: Splicing]] | [[Category: Splicing]] | ||
Revision as of 04:20, 25 December 2014
Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L)
| |||||||||||
Categories: Homo sapiens | Li, X | Liu, Y W | Niu, L W | Teng, M K | Zeng, F X | Zhang, W J | Zhao, Y | Rna binding protein | Rna recognition motif | Splicing
