2bix

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[[Image:2bix.gif|left|200px]]<br /><applet load="2bix" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2bix.gif|left|200px]]
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caption="2bix, resolution 2.68&Aring;" />
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'''CRYSTAL STRUCTURE OF APOCAROTENOID CLEAVAGE OXYGENASE FROM SYNECHOCYSTIS, FE-FREE APOENZYME'''<br />
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{{Structure
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|PDB= 2bix |SIZE=350|CAPTION= <scene name='initialview01'>2bix</scene>, resolution 2.68&Aring;
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|SITE= <scene name='pdbsite=AC1:Ote+Binding+Site+For+Chain+B'>AC1</scene>
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|LIGAND= <scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURE OF APOCAROTENOID CLEAVAGE OXYGENASE FROM SYNECHOCYSTIS, FE-FREE APOENZYME'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2BIX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.] with <scene name='pdbligand=C8E:'>C8E</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Ote+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIX OCA].
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2BIX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIX OCA].
==Reference==
==Reference==
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The structure of a retinal-forming carotenoid oxygenase., Kloer DP, Ruch S, Al-Babili S, Beyer P, Schulz GE, Science. 2005 Apr 8;308(5719):267-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15821095 15821095]
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The structure of a retinal-forming carotenoid oxygenase., Kloer DP, Ruch S, Al-Babili S, Beyer P, Schulz GE, Science. 2005 Apr 8;308(5719):267-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15821095 15821095]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Synechocystis sp.]]
[[Category: Synechocystis sp.]]
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[[Category: retinal formation]]
[[Category: retinal formation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:38:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:02:38 2008''

Revision as of 14:02, 20 March 2008

Image:2bix.gif


PDB ID 2bix

Drag the structure with the mouse to rotate
, resolution 2.68Å
Sites:
Ligands: and
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF APOCAROTENOID CLEAVAGE OXYGENASE FROM SYNECHOCYSTIS, FE-FREE APOENZYME


Overview

Enzymes that produce retinal and related apocarotenoids constitute a sequence- and thus structure-related family, a member of which was analyzed by x-ray diffraction. This member is an oxygenase and contains an Fe2+-4-His arrangement at the axis of a seven-bladed beta-propeller chain fold covered by a dome formed by six large loops. The Fe2+ is accessible through a long nonpolar tunnel that holds a carotenoid derivative in one of the crystals. On binding, three consecutive double bonds of this carotenoid changed from a straight all-trans to a cranked cis-trans-cis conformation. The remaining trans bond is located at the dioxygen-ligated Fe2+ and cleaved by oxygen.

About this Structure

2BIX is a Single protein structure of sequence from Synechocystis sp.. Full crystallographic information is available from OCA.

Reference

The structure of a retinal-forming carotenoid oxygenase., Kloer DP, Ruch S, Al-Babili S, Beyer P, Schulz GE, Science. 2005 Apr 8;308(5719):267-9. PMID:15821095

Page seeded by OCA on Thu Mar 20 16:02:38 2008

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