1xi3
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xi3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XI3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xi3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XI3 FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thiE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thiE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr> |
- | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-phosphate_diphosphorylase Thiamine-phosphate diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.3 2.5.1.3] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-phosphate_diphosphorylase Thiamine-phosphate diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.3 2.5.1.3] </span></td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xi3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xi3 RCSB], [http://www.ebi.ac.uk/pdbsum/1xi3 PDBsum], [http://www.topsan.org/Proteins/SECSG/1xi3 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xi3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xi3 RCSB], [http://www.ebi.ac.uk/pdbsum/1xi3 PDBsum], [http://www.topsan.org/Proteins/SECSG/1xi3 TOPSAN]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/THIE_PYRFU THIE_PYRFU]] Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Pyrococcus furiosus]] | [[Category: Pyrococcus furiosus]] | ||
[[Category: Thiamine-phosphate diphosphorylase]] | [[Category: Thiamine-phosphate diphosphorylase]] | ||
- | [[Category: Adams, M W.W | + | [[Category: Adams, M W.W]] |
- | [[Category: Chang, S H | + | [[Category: Chang, S H]] |
- | [[Category: Chen, L | + | [[Category: Chen, L]] |
- | [[Category: Dillard, B D | + | [[Category: Dillard, B D]] |
- | [[Category: Eneh, J C | + | [[Category: Eneh, J C]] |
- | [[Category: Habel, J | + | [[Category: Habel, J]] |
- | [[Category: Hopkins, R C | + | [[Category: Hopkins, R C]] |
- | [[Category: II, F L.Poole | + | [[Category: II, F L.Poole]] |
- | [[Category: III, W B.Arendall | + | [[Category: III, W B.Arendall]] |
- | [[Category: Jenney, F E | + | [[Category: Jenney, F E]] |
- | [[Category: Kelley, L L.C | + | [[Category: Kelley, L L.C]] |
- | [[Category: Lee, D | + | [[Category: Lee, D]] |
- | [[Category: Lee, H S | + | [[Category: Lee, H S]] |
- | [[Category: Li, T | + | [[Category: Li, T]] |
- | [[Category: Lin, D | + | [[Category: Lin, D]] |
- | [[Category: Liu, Z J | + | [[Category: Liu, Z J]] |
- | [[Category: Richardson, D C | + | [[Category: Richardson, D C]] |
- | [[Category: Richardson, J S | + | [[Category: Richardson, J S]] |
- | [[Category: Rose, J P | + | [[Category: Rose, J P]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Shah, C | + | [[Category: Shah, C]] |
- | [[Category: Sugar, F J | + | [[Category: Sugar, F J]] |
- | [[Category: Tempel, W | + | [[Category: Tempel, W]] |
- | [[Category: Wang, B C | + | [[Category: Wang, B C]] |
- | [[Category: Zhou, W | + | [[Category: Zhou, W]] |
[[Category: Hyperthermophile]] | [[Category: Hyperthermophile]] | ||
- | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
- | + | ||
- | + | ||
[[Category: Secsg]] | [[Category: Secsg]] | ||
- | [[Category: Southeast collaboratory for structural genomic]] | ||
- | [[Category: Structural genomic]] | ||
[[Category: Thiamine phosphate pyrophosphorylase]] | [[Category: Thiamine phosphate pyrophosphorylase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] |
Revision as of 04:33, 25 December 2014
Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001
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Categories: Pyrococcus furiosus | Thiamine-phosphate diphosphorylase | Adams, M W.W | Chang, S H | Chen, L | Dillard, B D | Eneh, J C | Habel, J | Hopkins, R C | II, F L.Poole | III, W B.Arendall | Jenney, F E | Kelley, L L.C | Lee, D | Lee, H S | Li, T | Lin, D | Liu, Z J | Richardson, D C | Richardson, J S | Rose, J P | Structural genomic | Shah, C | Sugar, F J | Tempel, W | Wang, B C | Zhou, W | Hyperthermophile | PSI, Protein structure initiative | Secsg | Thiamine phosphate pyrophosphorylase | Transferase