2xiv
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xiv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xiv RCSB], [http://www.ebi.ac.uk/pdbsum/2xiv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xiv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xiv RCSB], [http://www.ebi.ac.uk/pdbsum/2xiv PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/O53168_MYCTU O53168_MYCTU]] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Pogenberg, V | + | [[Category: Pogenberg, V]] |
| - | [[Category: Tizzano, B | + | [[Category: Tizzano, B]] |
| - | [[Category: Wilmanns, M | + | [[Category: Wilmanns, M]] |
[[Category: Cell wall]] | [[Category: Cell wall]] | ||
[[Category: Chap domain]] | [[Category: Chap domain]] | ||
Revision as of 04:35, 25 December 2014
STRUCTURE OF RV1477, HYPOTHETICAL INVASION PROTEIN OF MYCOBACTERIUM TUBERCULOSIS
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