4kp7
From Proteopedia
(Difference between revisions)
| Line 9: | Line 9: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kp7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kp7 RCSB], [http://www.ebi.ac.uk/pdbsum/4kp7 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kp7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kp7 RCSB], [http://www.ebi.ac.uk/pdbsum/4kp7 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DXR_PLAFX DXR_PLAFX]] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<ref>PMID:10477522</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 04:35, 25 December 2014
Structure of Plasmodium IspC in complex with a beta-thia-isostere derivative of Fosmidomycin
| |||||||||||
Categories: 1-deoxy-D-xylulose-5-phosphate reductoisomerase | Plafx | Bacher, A | Groll, M | Kunfermann, A | Apicoplast | Drug optimization | Dxp pathway | Malaria | Nadph binding | Non-covalent inhibition | Oxidoreductase-oxidoreductase inhibitor complex | Reductoisomerase | Rossmann fold | Tuberculosis
