3i5g

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oy6|2oy6]], [[3i5f|3i5f]], [[3i5h|3i5h]], [[3i5i|3i5i]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oy6|2oy6]], [[3i5f|3i5f]], [[3i5h|3i5h]], [[3i5i|3i5i]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MLE_TODPA MLE_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. [[http://www.uniprot.org/uniprot/MLR_TODPA MLR_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Doryteuthis pealeii]]
[[Category: Doryteuthis pealeii]]
[[Category: Todarodes pacificus]]
[[Category: Todarodes pacificus]]
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[[Category: Brown, J H.]]
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[[Category: Brown, J H]]
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[[Category: Cohen, C.]]
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[[Category: Cohen, C]]
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[[Category: Gourinath, S.]]
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[[Category: Gourinath, S]]
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[[Category: Himmel, D M.]]
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[[Category: Himmel, D M]]
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[[Category: Kovacs, M.]]
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[[Category: Kovacs, M]]
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[[Category: Neall-Hennessey, E O.]]
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[[Category: Neall-Hennessey, E O]]
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[[Category: Nyitray, L.]]
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[[Category: Nyitray, L]]
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[[Category: Reshetnikova, L.]]
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[[Category: Reshetnikova, L]]
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[[Category: Reutzel, R.]]
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[[Category: Reutzel, R]]
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[[Category: Szent-Gyorgyi, A G.]]
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[[Category: Szent-Gyorgyi, A G]]
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[[Category: Yang, Y.]]
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[[Category: Yang, Y]]
[[Category: Contractile protein]]
[[Category: Contractile protein]]
[[Category: Muscle myosin]]
[[Category: Muscle myosin]]
[[Category: Rigor-like]]
[[Category: Rigor-like]]
[[Category: Squid]]
[[Category: Squid]]

Revision as of 04:41, 25 December 2014

Crystal structure of rigor-like squid myosin S1

3i5g, resolution 2.60Å

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