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3i5g
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br> | <table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oy6|2oy6]], [[3i5f|3i5f]], [[3i5h|3i5h]], [[3i5i|3i5i]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oy6|2oy6]], [[3i5f|3i5f]], [[3i5h|3i5h]], [[3i5i|3i5i]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MLE_TODPA MLE_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. [[http://www.uniprot.org/uniprot/MLR_TODPA MLR_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Doryteuthis pealeii]] | [[Category: Doryteuthis pealeii]] | ||
[[Category: Todarodes pacificus]] | [[Category: Todarodes pacificus]] | ||
| - | [[Category: Brown, J H | + | [[Category: Brown, J H]] |
| - | [[Category: Cohen, C | + | [[Category: Cohen, C]] |
| - | [[Category: Gourinath, S | + | [[Category: Gourinath, S]] |
| - | [[Category: Himmel, D M | + | [[Category: Himmel, D M]] |
| - | [[Category: Kovacs, M | + | [[Category: Kovacs, M]] |
| - | [[Category: Neall-Hennessey, E O | + | [[Category: Neall-Hennessey, E O]] |
| - | [[Category: Nyitray, L | + | [[Category: Nyitray, L]] |
| - | [[Category: Reshetnikova, L | + | [[Category: Reshetnikova, L]] |
| - | [[Category: Reutzel, R | + | [[Category: Reutzel, R]] |
| - | [[Category: Szent-Gyorgyi, A G | + | [[Category: Szent-Gyorgyi, A G]] |
| - | [[Category: Yang, Y | + | [[Category: Yang, Y]] |
[[Category: Contractile protein]] | [[Category: Contractile protein]] | ||
[[Category: Muscle myosin]] | [[Category: Muscle myosin]] | ||
[[Category: Rigor-like]] | [[Category: Rigor-like]] | ||
[[Category: Squid]] | [[Category: Squid]] | ||
Revision as of 04:41, 25 December 2014
Crystal structure of rigor-like squid myosin S1
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