2d5b
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2d5b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D5B FirstGlance]. <br> | <table><tr><td colspan='2'>[[2d5b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D5B FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a8h|1a8h]], [[1woy|1woy]], [[2d54|2d54]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a8h|1a8h]], [[1woy|1woy]], [[2d54|2d54]]</td></tr> |
- | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d5b RCSB], [http://www.ebi.ac.uk/pdbsum/2d5b PDBsum], [http://www.topsan.org/Proteins/RSGI/2d5b TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d5b RCSB], [http://www.ebi.ac.uk/pdbsum/2d5b PDBsum], [http://www.topsan.org/Proteins/RSGI/2d5b TOPSAN]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8]] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Methionine--tRNA ligase]] | [[Category: Methionine--tRNA ligase]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
- | [[Category: Ishii, R | + | [[Category: Ishii, R]] |
- | [[Category: Konno, M | + | [[Category: Konno, M]] |
- | [[Category: Mori, Y | + | [[Category: Mori, Y]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Takasaka, R | + | [[Category: Takasaka, R]] |
- | [[Category: Takeda, R | + | [[Category: Takeda, R]] |
- | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Class 1a aar]] | [[Category: Class 1a aar]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
- | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
- | [[Category: Structural genomic]] |
Revision as of 04:43, 25 December 2014
Crystal Structure of Thermus Thermophilus Methionyl tRNA synthetase Y225F Mutant obtained in the presence of PEG6000
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