3rq3
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rq3 RCSB], [http://www.ebi.ac.uk/pdbsum/3rq3 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rq3 RCSB], [http://www.ebi.ac.uk/pdbsum/3rq3 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TIGIT_HUMAN TIGIT_HUMAN]] Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 04:51, 25 December 2014
Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) in hexagonal crystal form
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Categories: Homo sapiens | Almo, S C | Guo, H | IFN, Atoms-to-Animals:.The Immune Function Network | Structural genomic | Nathenson, S G | Ramagopal, U A | Rubinstein, R | Samanta, D | Adhesion | Atoms-to-animals: the immune function network | Ifn | Ig-domain | Immune receptor | Immune system | Nysgrc | Psi-biology | Tigit
