2acg
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2acg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ACG FirstGlance]. <br> | <table><tr><td colspan='2'>[[2acg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ACG FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5755 Acanthamoeba castellanii])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5755 Acanthamoeba castellanii])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2acg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2acg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2acg RCSB], [http://www.ebi.ac.uk/pdbsum/2acg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2acg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2acg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2acg RCSB], [http://www.ebi.ac.uk/pdbsum/2acg PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PROF2_ACACA PROF2_ACACA]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acanthamoeba castellanii]] | [[Category: Acanthamoeba castellanii]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Fedorov, A A | + | [[Category: Fedorov, A A]] |
| - | [[Category: Graupe, M H | + | [[Category: Graupe, M H]] |
| - | [[Category: Lattman, E E | + | [[Category: Lattman, E E]] |
| - | [[Category: Magnus, K A | + | [[Category: Magnus, K A]] |
| - | [[Category: Pollard, T D | + | [[Category: Pollard, T D]] |
[[Category: Actin-binding protein]] | [[Category: Actin-binding protein]] | ||
[[Category: Contractile protein]] | [[Category: Contractile protein]] | ||
[[Category: Profilin]] | [[Category: Profilin]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
Revision as of 05:00, 25 December 2014
ACANTHAMOEBA CASTELLANII PROFILIN II
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