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2bok

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[[Image:2bok.gif|left|200px]]<br /><applet load="2bok" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2bok.gif|left|200px]]
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caption="2bok, resolution 1.64&Aring;" />
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'''FACTOR XA- CATION'''<br />
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{{Structure
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|PDB= 2bok |SIZE=350|CAPTION= <scene name='initialview01'>2bok</scene>, resolution 1.64&Aring;
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|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=784:[AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM'>784</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6]
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|GENE=
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}}
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'''FACTOR XA- CATION'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2BOK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=784:'>784</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] Known structural/functional Site: <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BOK OCA].
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2BOK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BOK OCA].
==Reference==
==Reference==
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Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand., Scharer K, Morgenthaler M, Paulini R, Obst-Sander U, Banner DW, Schlatter D, Benz J, Stihle M, Diederich F, Angew Chem Int Ed Engl. 2005 Jul 11;44(28):4400-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15952226 15952226]
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Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand., Scharer K, Morgenthaler M, Paulini R, Obst-Sander U, Banner DW, Schlatter D, Benz J, Stihle M, Diederich F, Angew Chem Int Ed Engl. 2005 Jul 11;44(28):4400-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15952226 15952226]
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: serine protease]]
[[Category: serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:39:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:04:44 2008''

Revision as of 14:04, 20 March 2008

Image:2bok.gif


PDB ID 2bok

Drag the structure with the mouse to rotate
, resolution 1.64Å
Sites:
Ligands: and
Activity: Coagulation factor Xa, with EC number 3.4.21.6
Coordinates: save as pdb, mmCIF, xml



FACTOR XA- CATION


Disease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this Structure

2BOK is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand., Scharer K, Morgenthaler M, Paulini R, Obst-Sander U, Banner DW, Schlatter D, Benz J, Stihle M, Diederich F, Angew Chem Int Ed Engl. 2005 Jul 11;44(28):4400-4. PMID:15952226

Page seeded by OCA on Thu Mar 20 16:04:44 2008

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