1wi0

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wi0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wi0 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wi0 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wi0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wi0 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wi0 TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MP2K5_MOUSE MP2K5_MOUSE]] Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.<ref>PMID:10473620</ref> <ref>PMID:16507987</ref>
==See Also==
==See Also==
*[[Mitogen-activated protein kinase kinase|Mitogen-activated protein kinase kinase]]
*[[Mitogen-activated protein kinase kinase|Mitogen-activated protein kinase kinase]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi, F]]
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[[Category: Inoue, M.]]
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[[Category: Inoue, M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba, S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Tochio, N.]]
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[[Category: Tochio, N]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
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[[Category: Yoneyama, M.]]
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[[Category: Yoneyama, M]]
[[Category: Cytoplasmic signalling]]
[[Category: Cytoplasmic signalling]]
[[Category: Pb1 domain]]
[[Category: Pb1 domain]]
[[Category: Protein-protein interaction site]]
[[Category: Protein-protein interaction site]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 05:18, 25 December 2014

Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)

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